The Journal of Organic Chemistry欢迎有机化学基础研究的原创稿件，理论和实验研究皆可。特别值得注意的是： a. 单步或多步合成方法/全合成类的稿件希望能够展示在合成策略、转化、路线简化方面的概念新颖性，而不仅仅是将以前报道的化学反应扩展到不同的反应底物、试剂或催化剂。 b. 侧重于机理研究（实验或理论）的稿件应显示方法上的进步或提供对化学反应过程的新见解，而不仅仅是确认以前建立的机理。 c. 天然产物分离和鉴定研究应报告不寻常的骨架特征，结构测定方法的改进，或对生物合成途径的深入了解。 d. 含有生物研究、分析化学、功能分子和系统或材料科学元素的稿件应证明与所报告的有机化学部分有关的那些方面的新颖性。 The Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community. Manuscripts with a focus on the following topics along with guidance are included below. The scope of organic chemistry is broader than these several areas of research and the Editorial Board is consistently welcoming and evaluating manuscripts addressing topics in addition to these. Guidelines for specific focus areas are as follows: Single or multistep synthetic methods manuscripts and total synthesis manuscripts are expected to demonstrate strategies, transformations, or shortened routes to target structures that show conceptual novelty, not merely the extension of previously reported chemistry to a different class of reaction substrates, reagents, or catalysts. Manuscripts focusing on mechanistic studies (experimental or theoretical) should show methodological advances or provide novel insight into the course of chemical reactions, rather than only confirming previously established mechanisms. Natural products isolation and identification studies should report unusual skeletal features, improvements in methods for structural determination, or insights into biosynthetic pathways. Manuscripts with elements of biological study, analytical chemistry, functional molecules and systems, or materials science should demonstrate novelty in those aspects associated with the organic chemistry portion of the work being reported.