Matrix Biology was established in 1980 as Collagen and Related Research, an international scientific journal for publication of research on the extracellular matrix. The journal became Matrix (1989-1993) and then Matrix Biology in 1994 to reflect the expansion of knowledge and interest in the diversity of extracellular matrix-associated molecules and the increasing awareness of the importance of 'matrix' in development, health, and disease and its significance for biological processes. Matrix Biology is now the leading journal devoted to publishing the latest research results in extracellular matrix research that deal with molecular components of the extracellular matrix and biological impacts of cellular interactions with extracellular matrices. We welcome articles in any area of extracellular matrix research that provide new mechanistic insights or which challenge longstanding biological paradigms in the field of extracellular matrix research. Matrix Biology publishes original studies in, but not limited to, cell and molecular biology, developmental biology, genetics, structural biology, chronobiology, infection and immunity, immunology, virology, signalling, disease mechanisms, and therapeutics related to the extracellular matrix and cellular interactions with the extracellular matrix. Papers considered for peer-review must contain substantial advances supported by mechanistic and functional insights. In addition to original research articles, Matrix Biology welcomes highly impactful reviews. Please view our Guide for Authors for more information. Reasons to submit your next article to Matrix Biology: The premier journal in the field of extracellular matrix biology with impacts across many fields of biology and medicine. Published articles have a universal appeal, value, and utility to the researcher community worldwide. An international editorial board of key researchers in the field. Flexible publication: you can choose to publish open access. Your paper your way: no unnecessary formatting requests. No submission fees. No color page charges for online version. Matrix Biology Plus, a companion title to Matrix Biology, is an online-only, open access journal welcomes papers reporting novel findings, which provide a substantive advance in the field of matrix biology without a strict requirement for novel biological mechanisms.