The Mathematical Modelling and Numerical Simulation with Applications (MMNSA) is an international research journal, which publishes top-level original and review papers, short communications and proceedings on mathematical modelling in biology, engineering, medicine, chemistry, physics, and other areas. MMNSA focuses on research related to the mathematical modelling of engineering and environmental processes, manufacturing, and industrial systems. A significant emerging area of research activity involves interdisciplinary processes, and contributions in this area with numerical simulations are also encouraged. The scope of the journal is devoted to mathematical modelling with sufficiently advanced models, and the works studying mainly the existence and stability of stationary points of ODE systems without applications are not considered. The scope of the journal also includes applied mathematics and mathematical analysis in the context of its applications to real-world problems. The journal is essentially functioning on the basis of topical issues representing active areas of research. The authors are invited to submit papers to the announced issues or to suggest new issues. Journal publishes research articles and reviews within the whole field of mathematical modelling, and it will continue to provide information on the latest trends and developments in this ever-expanding subject.