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Canine Peripheral BloodPeripheral Immune SystemToll-like Receptor SignalingReceptor-mediated EndocytosisLC TreatmentAdaptive Immune ResponsesFlow Cytometry AnalysisPhosphatidylinositol 3-KinaseAntigen Presenting CellsMannose ReceptorPrimary ImmuneT Cell SubsetRegulatory T CellRegulatory T CellsClodronateMacropinocytosisWortmanninAPCSPhagocytosisAntigen