Osteoarthritis and Cartilage Open is the official open access journal of the Osteoarthritis Research Society International, and a companion title to the respected Osteoarthritis and Cartilage. Osteoarthritis and Cartilage Open is an international, fully peer-reviewed, multidisciplinary journal. It publishes findings from the basic, translational and clinical sciences in all fields of research of relevance to osteoarthritis, cartilage, and intervertebral disc. It also accepts clinical study protocols and manuscripts describing the large data sets obtained from experimental or clinical studies. The Journal fosters the cross-fertilization of findings from both the basic and clinical sciences of the various disciplines involved, including, but not limited to: Osteoarthritis. Cartilage and subchondral bone. Intervertebral disc. Tendons, ligaments and other musculoskeletal tissues. Molecular biology. Clinical pharmacology. Orthopaedics and traumatology. Rheumatology. Physical medicine. Biochemistry. Epidemiology.