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文献信息
Biopharmaceutics & Drug Dispositionpublishes original review articles, short communications, and reports in biopharmaceutics, drug disposition, pharmacokinetics and pharmacodynamics, especially those that have a direct relation to the drug discovery/development and the therapeutic use of drugs. These includes: - animal and human pharmacological studies that focus on therapeutic response. pharmacodynamics, and toxicity related to plasma and tissue concentrations of drugs and their metabolites, - in vitro and in vivo drug absorption, distribution, metabolism, transport, and excretion studies that facilitate investigations related to the use of drugs in man - studies on membrane transport and enzymes, including their regulation and the impact of pharmacogenomics on drug absorption and disposition, - simulation and modeling in drug discovery and development - theoretical treatises - includes themed issues and reviews and exclude manuscripts on - bioavailability studies reporting only on simple PK parameters such as Cmax, tmax and t1/2 without mechanistic interpretation - analytical methods
PHARMACOKINETICSPharmacokinetic ParametersOral AdministrationPlasma Concentration-time CurvePlasma ConcentrationIntravenous AdministrationMean Residence TimeTissue DistributionHealthy VolunteersPharmacokinetics and PharmacodynamicsOral BioavailabilityPlasma Protein BindingDrug InteractionRenal ClearanceRelative BioavailabilityBioavailabilityHuman Liver MicrosomesProtein BindingHealthy MaleAbsolute Bioavailability
vol.46 (2025)
vol.45 (2024)
vol.44 (2023)
vol.43 (2022)
vol.42 (2021)
vol.41 (2020)
vol.40 (2019)
vol.39 (2018)
vol.38 (2017)
vol.37 (2016)
vol.36 (2015)
vol.35 (2014)
vol.34 (2013)
vol.33 (2012)
vol.32 (2011)
vol.31 (2010)
vol.30 (2009)
vol.29 (2008)
vol.28 (2007)
vol.27 (2006)
vol.26 (2005)
vol.25 (2004)
vol.24 (2003)
vol.23 (2002)
vol.22 (2001)
vol.21 (2000)
vol.20 (1999)
vol.19 (1998)
vol.18 (1997)
vol.17 (1996)
vol.16 (1995)
vol.15 (1994)
vol.14 (1993)
vol.13 (1992)
vol.12 (1991)
vol.11 (1990)
vol.10 (1989)
vol.9 (1988)
vol.8 (1987)
vol.7 (1986)
vol.6 (1985)
vol.5 (1984)
vol.4 (1983)
vol.3 (1982)
vol.2 (1981)
vol.1 (1980)
vol.1 (1979)
ORIGINAL ARTICLE
LETTER TO THE EDITOR