The Journal of Mass Spectrometry and Advances in the Clinical Lab (JMSACL, formerly known as Clinical Mass Spectrometry) is an open access, pay-what-you-can journal and publishes peer-reviewed articles addressing mass spectrometry and other advances in Laboratory Medicine and Pathology with a focus on development of diagnostic and related applications, including data science, to improve patient outcomes and reduce healthcare costs. Beyond communication of the application of technologies in the routine clinical diagnostic setting, by publishing critically validated analytical protocols, the journal also addresses the translation of experimental techniques and analytical research into patient care, and the use of these technologies in clinical research and routine patient management. The scope of the journal is not restricted to any particular technology, but covers the entire range of technologies and advancements that are expected to impact the clinical lab. The journal encourages submissions having a clear path to patient care, including basic and translational research, and animal studies. Subject areas covered by the journal include, but are not restricted to: Automation Clinical Studies and Implementation Cross-Technology Investigations Data Science Endocrinology Error Sources, Risk Assessment and Patient Safety Glycomics Harmonization and Standardization Imaging Instrumentation Lipidomics Metabolomics and Metabolic Analyses Method Development and Validation Metrology Microbiology Neonatal Screening New Technologies Point-of-Care Technologies Protein Quantification Protein Variant Detection Proteomics Quality Management Reference Methods and Materials Regulatory Aspects in Diagnostic Applications Sample Preparation Separation Science Small Molecules Therapeutic Drug Monitoring Toxicology Types of papers: Reviews, graphical reviews, mini-reviews, original research papers, short communications (e.g., letters, case studies, protocols, application notes, developed poster presentations), guidelines and best practice documents, tutorials, invited editorials, opinions.